Disease Concepts in North America

Rheumatic Disease Clinics of North America

Ankylosing Spondylitis and related spondyloarthropathies form a family of rheumatic diseases that are characterized by inflammatory peripheral and axial arthritis, with predilection for sacroiliitis, and a remarkably strong association with a genetic marker, HLA-B27. The association with B27 has provided a great impetus to the epidemio-logic studies of spondyloarthropathies and also helped broa...

Chronic wasting disease in deer and elk in North America.

Chronic wasting disease (CWD) has emerged as an important disease of wildlife in North America. The disease is a unique member of the transmissible spongiform encephalopathies (TSEs) or prion diseases, which naturally affect only a few species. Of the TSEs, CWD is the only one found in free-ranging species. However, interest in CWD has recently grown, by association with the better-known TSEs s...

Highlight on Advances in Nontuberculous Mycobacterial Disease in North America

Nontuberculous mycobacteria (NTM) are ubiquitous in the environment and exist as an important cause of pulmonary infections in humans. Pulmonary involvement is the most common disease manifestation of NTM and the incidence of NTM is growing in North America. Susceptibility to NTM infection is incompletely understood; therefore preventative tools are not well defined. Treatment of pulmonary nont...

Admixture in North America

The history of North America has been marked by the encounter of populations from different continents. The discovery of the New World began a period defined by human migrations at a much larger scale than in previous history. This movement of people, voluntary or forced, changed profoundly the human landscape. As populations came into contact, admixture followed in varying degrees depending on...

Medicine in North America